This conference begins with a discussion of RNA as the “new” central molecule of molecular biology. Sam follows with a review of coding DNA which leads to a discussion of the “new” non-coding DNA genes. He also looks at miRNA and siRNA and how they are being used in medical research.
The Comparative Genomics section compares the human genome to birds, rodents, chimps and Neanderthals. He also takes a look at the genomes of HIV and H1N1 and the DNA identification of the Romanov skeletons.
Cloning and Stem Cells come next. Sam reviews the history and updates the status of each. The emphasis is on iPSCs and how they are being used in medical research.
Sam finishes with an update on cancer research. He emphasizes the ultimate goal—the elimination of cancer stem cells.
Recorded in 2010
Conference Notes and PowerPoint Slides
To help you follow along with the videos, please review the PowerPoint slides.
- Centrality of RNA (00:00:36)
- Human Genome (00:05:53)
- DNA / RNA Review (00:24:44)
- Coding DNA Gene Expression (00:35:20)
- Non-Coding DNA Gene Expression (00:53:34
- “RISC” and “Dicer” (01:06:55)
- miRNA Production (01:12:04)
- ONCOmiRs (01:25:08)
- Medical Applications Using Backward Gene Production (01:32:26)
- How to Join the Team (01:50:28)
- Comparative Genomics (01:55:33)
- Cloning and Stem Cells (02:28:20)
- Therapeutic Cloning and Stem Cells (03:08:06)
- Reprogramming (iPS) (03:28:00)
- Cancer Stem Cells (03:45:29)