NOTE: This is not meant to be a Bibliography!

NCBI: www.ncbi.nlm.nih.gov
OMIM - details of over 18,000 genetic conditions > onc and TSG
Coffee Break - Genes & Disease > Cancer
CGAP - Cancer Genome Anatomy Project
National Cancer Institute www.cancer.gov/
American Cancer Society Statistics: http://www.cancer.org/
Female v. Male - Estimated New Cases - Estimated Deaths for 2007
New Genome Sequencing - 1000 subjects: Science NOW Daily News, Jan 22, 2008
Carcinogens: http://ntp.niehs.nih.gov/index.cfm?objectid=72016262-BDB7-CEBA-FA60E922B18C2540
20,000 Human Protein Genes - Francis Collins at NABT in Atlanta, Dec 1, 2007
$1000 Genome Evaluation - Wired, December 2007
Know Your DNA - Genomes for All: Scientific American, January 2006
Owning the Stuff of Life - Patenting Genes: Scientific American, Feb. 2006
Time for a Human Interactome Project?: The Scientist, March 2006
Analysis of Human Interactome: Nature Genetics, March 2006
DNA is Not Your Destiny - Environmental Methylation - Discover, November 2006
MicroRNAs: Biology, Func., & Expression - Neil Clarke & Phillipe Sanseau - 2007
MicroRNAs: An Emerging Portrait: The Scientist - October, 2007
MicroRNAs: Collection - Nature Reviews: October, 2007
Strategies for Silencing Human Disease RNAi: Nature Rev. Genetics, March 2007
Brain-Specific miRNA Regulates Dendritic Spine Develop: Nature, Jan 19, 2006
MicroRNAs: Expression Signature of Solid Tumor: PNAS, ol, February 3, 2006
The Colorectal microRNAome: PNAS, ol, February 27, 2007
Tumor Formation Illustrations: Scientific American, September 1996
High Fat Diet and Cancer Risk: USA Today, November 1, 2007, pp.1
Smoking in Adolescent Females - risk for Breast Cancer: Lancet, Oct 5. 2002
Alcohol and Breast Cancer: European Cancer Conference, September 27, 2007
Genomic Landscapes - Human Breast & Colorectal Cancers: Science Nov 16, 2007
Mapping the Cancer Genome: Scientific American, March, 2007
Human Variome Project: Nature Genetics, April 2007
Vaccinia Virus Destroys Liver Cancer Cells: Clinical Investigations, Oct. 25, 2007
Chromosomal Chaos and Cancer: Scientific American, May, 2007

Cloning and Stem Cells

Dolly - Reproductive Clone: Nature, February 27, 1997
Poor Reproductive Cloning Results - Imprints: Science - July 6, 2001
Stem Cell Challenge: Scientific American - June 2004
First Human Embryonic Stem Cells in Lab: Science, Nov 6, 1998 - U. Wisconsin
"Ethical" Embryo Stem Cells:
ES from Single Blastomere - Seven Cells > Normal Fetus: Nature - Aug. 23, 2006
Altered Nuclear Transfer - knock out Cdx2 - no implant: Nature - Oct 20, 2005
Utilize 'Dead' Embryo Cells: Science, September 29, 2006
Parthenogenesis: Double Female - 46 female chromosomes / 0 male
DeDifferentiation - iPS with Oct 3/4, Sox2, c-Myc, Klf4: Cell - August 25, 2006
Confirmed:
Yamanaka - Induced Pluripotent Stem Cells: Nature, July 19, 2007
Jaenisch - Reprogramming to Pluripotent State: Nature, July 19, 2007
Hochedlinger - Reprogrammed Fibroblasts: Cell Stem Cell, July, 2007
Human:
Cell (OL) Nov. 20, 2007 - Yamanaka: OCT 3/4, SOX2, KLF4, c-MYK
Science (OL) Nov. 20, 2007 - Thomson: OCT4, SOX2, NANOG, LIN28
Correct Sickle cell in Mouse with iPs: Science (OL) December 6, 2007
Ideal Stem Cell:
Easy Access
Timely Access
No Tumor Risk
Pluripotent - 220
'Home'
Non-Immunogenic
The AMAZING MSCs:
Adult Mesenchymal Stem Cells
Help success of bone marrow / BM transplant - helps prevent GVHD
ADSC = Adipose Derived Stem Cells; biopsy to coronary artery - 90 minutes
Amniocytes - prenatal diagnosis and T.E. heart valve
Prenatal diagnosis - Osteogenesis Imperfecta in utero therapy - parental MSCs
Expand in vitro, infect with Interferon Beta, 'Home' to Tumor - Deliver drug
Adult Mesenchymal Stem Cells:
Regenerative Medicine' International Conference
Cleveland Marriott Downtown at Key Center - August 27 - 29, 2007

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